DEGENERATIVE DISC DISEASE

Many patients diagnosed with degenerative disc disease wonder what this diagnosis means for them. Some may define the term "degenerative" as a process that worsens over time; others will define the term "disease" as a destructive process uninhibited by treatment.

Although the term degenerative usually signifies a process which worsens with age, one can feel confident that in most cases the associated pain with the degenerative process lessens over time. As we age proteins inside the disc eventually dry up, and the discs become stiffer; in many people these results in less pain by the time they are in their sixties. Also of note, is that degenerative disc disease is not a disease at all, but rather a degenerative condition in which your discs lose their flexibility and ability to cushion your spine. This condition may eventually lead to pain that is quite variable in nature and severity.

The lumbar disc is a unique and well-designed structure in the spine. It is strong enough to resist terrific forces in multiple different planes of motion, yet it is still very mobile. Everything you do during the day - once you stand upright - begins to test the spine's ability to support your body weight. Over time, these repeated daily stresses and minor injuries can add up and begin to affect the discs in your spine. Minor injuries to the disc may occur and not cause pain at the time of the injury. However, as they add up, the disc eventually begins to suffer from the wear and tear - it begins to degenerate.

Pathophysiology

In order to understand your symptoms and treatment choices, you should start with an understanding of the general anatomy of your lumbar spine (lower back). This includes becoming familiar with the various parts that make up the spine and how these parts work together (Please review "Basic Back Anatomy").

With degenerative disc disease, the main problem lies within one or more of the intervertebral discs. There is a disc between each of the vertebra in your spine. The intervertebral discs are designed to absorb pressure and keep the spine flexible by acting as cushions during body movement similar to shock absorbers. Without the cushion effect of the discs, the vertebrae in your spine would not be able to absorb stresses, or provide the movement needed to bend and twist.

Normal intervertebral discs are well hydrated, the nucleus containing 80-85% water and the annulus about 80%. The water content gives the nucleus a spongy quality and allows it to absorb spinal stress. Excessive pressure or injuries to the disc can cause injury to the annulus - the outer ring of tough ligament material that holds the vertebrae together.

Generally, the annulus is the first portion of the disc that seems to be injured. Small tears show up as in the ligament material of the annulus. These tears heal by scar tissue which is not as strong as normal ligament tissue. Over time, as more scar tissue forms, the annulus becomes weaker; the disc becomes more and more dehydrated and denitrified. If the disc had a normal blood supply, this water and nutrient loss would be replaced and reparative changes noted. Unfortunately, the disc does not have a direct blood supply and thus its reparative powers are diminished.

Because of water and nutrient loss, the discs lose some of their ability to act as a cushion. This can lead to even more stress on the annulus and still more tears as the cycle repeats itself. As the nucleus loses its water content it collapses, allowing the two vertebrae above and below to move closer to one another. This results in a narrowing of the disc space between the two vertebrae and creates multiple anatomical changes. With less space available, the nerve roots in the neuroforamen may become compressed, causing them to swell and signal pain. Facet joints located at the back of the spine are forced to shift which may lead to facet syndrome. The disc itself is weakened and may lose its ability to absorb stress and provide support eventually leading to disc bulging or herniation. Pieces of the damaged disc may also break off and cause irritation of the nerves.

Bone spurs, sometimes called osteophytes, may begin to form around the disc space. These bones spurs can also form around the facet joints and are thought to be due to the body's response to try to stop the excess motion at the spinal segment. The bone spurs can become a problem if they start to grow into the spinal canal and press into your spinal cord and nerves. Hypertrophy or enlargement of the ligaments and facets occur as they try to compensate for the additional stress noted above. This over-growth causes the spinal canal to narrow (spinal stenosis), which can compress the spinal cord and nerves causing pain.

Symptoms

In trying to understand the symptoms associated with degenerative disc disease it is important to understand the term Diskogenic Pain. Diskogenic pain is a term back specialists use when referring to pain caused by a damaged intervertebral disc. As the disc begins to degenerate, there is some evidence that the disc itself becomes painful. Movements that place stress on the disc can result in back pain that appears to come from the disc. This is similar to any other body part that is injured, such as a broken bone, or even a cut in the skin. When these types of injuries are held still there is no pain. However, if you move a broken bone, or the skin around a cut, it causes pain.

Diskogenic pain usually causes pain felt in the lower back. It may also feel like the pain is coming from your buttock areas and even down into the upper thighs. The experience of feeling pain in an area away from the cause of the pain - is common in many areas of the body. Examples include: a person who has gallstones may feel the pain in their shoulder; or a person experiencing a heart attack may feel pain in the left arm. This is referred to as radiation of the pain. It is very common for pain produced by spine problems, such as disc problems, to be felt in different areas of the body, including the back itself.

The symptoms of degenerative disc disease vary from person to person. Many people with deterioration have no pain, while others may experience pain that is naggingly irritating to severely debilitating. Interestingly, even though this condition affects people starting in their twenties or thirties, people in their sixties are less likely to have back pain caused by deteriorated discs. This is thought to be a result of a decrease in inflammatory proteins within the disc space, the stiffening of the disc and a decrease of micro-motion.

The typical individual with degenerative disc disease is an active and otherwise healthy person. Common symptoms include:

• The pain is generally made worse with sitting, since in the seated position the lumbosacral discs are loaded more than when standing.
• Certain types of activity will usually worsen the pain, especially bending, lifting and twisting.
• Walking, and even running, may actually feel better than prolonged sitting or standing.
• Patients will generally feel better if they can change positions frequently, and lying down is usually the best position since this relieves stress on the disc space.
• Most patients will have some underlying chronic low back pain, with intermittent episodes of severe low back pain. The exact cause of these severe episodes of pain is not known, but it has been theorized that it is due to abnormal micro-motion in the degenerated disc that spurs an inflammatory reaction. In an attempt to stabilize the spine and decrease the micro-motion, the body reacts to the disc pain with muscle spasms. The reactive spasms are what make patients feel like their back has "gone out".
• The severe episodes of back pain will generally last from a few days to a few months before the patient goes back to their baseline level of chronic pain. The amount of pain is quite variable and can range from a nagging level of irritation to severe and disabling pain. In addition to low back pain, there may be leg pain, numbness and tingling. Even without pressure on the nerve root (a "pinched nerve"), other structures in the back can refer pain down the buttocks and into the legs. The nerves can become sensitized with inflammation from the proteins within the disc space and produce the sensation of numbness/tingling. Generally, the pain does not go below the knee.
These sensations, although worrisome and annoying, rarely indicate that there is any ongoing nerve root damage. However, any weakness in the leg muscles (such as foot drop) is an indicator of some nerve root damage.

How is the diagnosis made?

When you first experience pain, consult your family doctor. Your doctor will take a complete medical history to understand your symptoms, any prior injuries or conditions, and determine whether any lifestyle habits are causing the pain. Next, a physical exam is performed to determine the source of the pain and test for any muscle weakness or numbness. Your doctor may order one or more of the following imaging studies: X-ray, MRI scan, disco gram, myelogram, or CT scan to identify a tumor, herniated disc, degenerative disc disease or other conditions that compress the nerve roots (see section on testing).

NONSURGICAL TREATMENTS

Nonsurgical treatment for degenerative disc disease may include rest and self care. If the pain persists and becomes chronic, other therapies such as intradiscal decompression, reduction and stabilization using the DRX 9000 / 9500, Vax-D (see section on Low Back and Neck Pain), physical therapy that focuses on biomechanical and postural correction, core stabilization, aquatic therapy, medication, home exercises, hydrotherapy etc.

Specific Rest

Immediately after a back injury, rest is often all your back needs to feel better. Rest is used to take the pressure off your spine and the muscles around it. You should rest in a comfortable position on a firm mattress. Placing a pillow under your knees can also help relieve pain. Do not stay in bed for several days! Bed rest for more than two or three days can weaken the back muscles, making the problem worse instead of better. Even though you may still feel some pain, a gradual return to normal activities is good for your muscles. In most cases of sudden back pain, the sooner you start moving again, the sooner your back pain will improve. Ice and heat may also be utilized and one should start performing some basic low back stretching exercises (see section under "Basic back stretching exercises”).

Self Care

Using correct posture and keeping your spine in alignment are the most important things you can do for your back. You may need to make adjustments to your daily standing, sitting, and sleeping habits. You may also need to learn proper ways to lift and bend. Your workspace may need to be rearranged to keep your spine from being under stress.

Stress is the number one obstacle to pain control. Pain increases when you are tense and stressed. Relaxation exercises are one way of reclaiming control of your body. Deep breathing, visualization, and other relaxation techniques can help you to better manage the pain you live with.

Intradiscal Decompression

Spinal experts have known and taught for decades that discs, in a compressed, anaerobic state find it next to impossible to heal. However, through intradiscal decompression, negative pressure is created inside the disc. In real simple terms, this negative pressure increases the diffusion rate of vitamins, minerals, oxygen, water and other collagen precursors that are needed to rebuild the collagen matrix of the disc. This process assists in the healing process of the disc (Please see the Low Back and Neck pain section of our website).

Physical Therapy

Postural asymmetries across the pelvic girdle, hips, spine, rib cage and shoulder complex will be assessed and treated in association with the work done on the DRX 9000. This type of in-depth biomechanical assessment allows accurate diagnosis of any underlying structural issues that may be contributing to a patient's often complicated and chronic problem. Exercise and work patterns will also be assessed and changed as necessary. Other types of treatments may include:

Modalities - alternating heat and ice, massage, ultrasounds, and electric stimulation

Bracing - ranging from a simple corset to a rigid plastic body jacket

Flexibility and Strength Training - this is achieved through exercises, posture retraining, stretching, etc.

Posture Training - learning how to stand, sit, and move properly; incorrect posture can contribute to back pain

Core Stabilization

Aquatic Therapy

Aquatic Therapy is a system of exercises and activities designed to utilize water’s unique healing benefits. In the rehabilitation process, the buoyancy of water helps to reduce joint compression. Following injury or surgery, range of motion and weight bearing exercises can be initiated more quickly without causing undue stress to the healing tissues and bone. The high density of water also creates increased resistance against movement, thus providing more feedback and increased effectiveness of strengthening exercises. Aquatic therapy has been proven as an effective treatment and rehabilitation medium for many health conditions.

Exercise

Exercise is vital to recovery and to maintaining a healthy spine. Consider it part of long-term health management and risk reduction. Regular exercise is the most basic way to combat back problems. However, if you an acute injury to the spine talk to your doctor or physical therapist before you start an exercise routine. You need to make sure the exercises you choose are effective and safe for your particular case.

Why exercise? Scientific studies have shown that people who exercise regularly have far fewer problems with their back. It helps strengthen the muscles in your back that correspond with your spine. It can reduce your risk of falls and injuries. It can strengthen your abdomen (your belly), arms, and legs, which reduces back strain. Stretching reduces risk of muscle spasms. In addition, weight bearing exercises help prevent loss of bone mass caused by osteoporosis, reducing your risk of compression fractures. Aerobic exercise, the type that gets your heart pumping and pulse rate up, has been shown to be a good pain reliever as well. The natural chemicals of the body that combat pain - called endorphins - are released during exercise and actually reduce your pain.

Medications

Your doctor may prescribe pain relievers to include: no steroidal anti-inflammatory medications (NSAIDs), steroids, non-narcotic analgesics, narcotics or muscle relaxers. No steroidal anti-inflammatory drugs (NSAIDs) - aspirin, naproxen (Naprosyn, Aleve), ibuprofen (Motrin, Nuprin, and Advil), celecoxib (Celebrex) are examples of no steroidal anti-inflammatory drugs used to reduce inflammation and relieve pain. However, be aware that NSAIDs can decrease renal function and excessive use can lead to kidney problems. Heavy use of NSAIDs may also lead to GI complications (i.e. ulcers).

Steroids can be used to reduce the swelling and inflammation of the nerves. They are taken orally (as a Medrol dose pack) or generic prednisone in a tapering dosage over a 5-10 period. Steroids may also be given as an injection directly into the source of pain. Usually, it takes 24 hours for Steroids to take affect.

Analgesics, such as acetaminophen (Tylenol) can relieve pain but don't have the anti-inflammatory effects of NSAIDs or steroids.

Narcotic Pain Medications: If you experience severe pain, your health provider might prescribe a narcotic pain medication such as codeine or morphine. Narcotics relieve pain by acting as a numbing anesthetic to the central nervous system. The strength and length of pain relief differs for each drug. Narcotics can cause related side effects such as nausea, vomiting, constipation, and sedation or drowsiness. These side effects are predictable and can often be prevented. Common preventative measures include: not taking sleeping aids or antidepressants in conjunction with narcotics, avoiding alcohol, increasing fluid intake, eating a high fiber diet, and using a fiber laxative or stool softener to treat constipation. Remember that narcotics can be addictive if used excessively or improperly.

Muscle Relaxants (i.e. Flexeril, Skelaxin): If you are having muscle spasms, muscle relaxants can help relieve pain, but they are only shown to be marginally effective. They also have a significant risk of drowsiness and depression. Long-term use is not suggested; only 5-10 days is typically recommended.

Holistic Therapies

Some patients want to try holistic therapies such as acupuncture, acupressure, nutritional supplements, and biofeedback. The effectiveness of these treatments for degenerative disc disease may aid you in learning coping mechanisms for managing pain as well as improving your overall health. For resources in your area visit:

National Center for Complementary and Alternative Medicine (NCCAM) nccam.nih.gov
Ask NOAH About: Alternative (Complementary) Medicine
www.noah-health.org/english/alternative/alternative.html
Whole Health MD www.WholeHealthMD.com
The Natural Pharmacist www.tnp.com

(The Rejuvenation Center does not endorse these sites. They are provided as a resource only.)

SURGICAL TREATMENTS

Surgery is rarely recommended unless you have a proven instability and your symptoms do not significantly improve with nonsurgical treatments. The goal of surgery is to stop the movement of the painful motion segment and decompress any spinal nerves. Talk to your doctor about whether surgery is right for you. Some surgeries specific to degenerative disc disease are:

Interbody Fusion is a surgical procedure in which one or more of the bony vertebrae of the spine are permanently joined together to provide stability to the spine. Spinal fusion can be performed at any level of the spine but is most common in the lumbar and cervical regions where it is most moveable. At each level of the spine, there is a disc space in the front and paired facet joints in the back (see Basic Back Anatomy). Working together, these structures define a motion segment and permit range of motion. Two vertebral segments need to be fused to stop the motion at one segment.

Intradiscal Electro thermal Therapy (IDET) uses a thin catheter to deliver heat directly into the spinal discs to shrink the tears and fissures in the annulus and thermo-coagulate nerves to overcome diskogenic back pain.




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